Summary

In the Cheng lab, we strive to understand the fundamental questions of how RNA regulation controls cellular processes in normal biology and in the context of cancer. Working at the interface of RNA splicing and breast cancer biology, our current focus is on regulation of breast cancer metastasis driven by alternative splicing. We use molecular biology, genomics, and bioinformatics approaches in conjunction with genetic models and patient samples to discover rules and networks that regulate metastasis and associated processes. We work closely with physician scientists and aim to apply our findings from basic research to the development of prognostic markers and therapeutics for the treatment of breast cancer.

We are seeking individuals who are interested in RNA binding proteins, RNA regulation, transposon elements, circulating tumor cells, and breast cancer metastasis. Candidates with experience in RNA biology or mouse models are strongly preferred. We employ a wide range of cutting-edge techniques including single-cell RNA sequencing, long-reads sequencing, CRISPR-mediated barcoding, and CTC imaging. We also offer enormous opportunities to conduct wet-lab and dry-lab approaches within the lab. This is an exceptional opportunity for a highly motivated individual to experience research freedom in a highly supportive environment.

Job Duties

• Conduct Experiments: Design, execute experiments, and analyze data.
• Research Publications: Prepare and submit research papers and reviews.
• Productivity: Maintain high levels of productivity, ensuring timely completion of research projects.
• Grant Submissions: Assist the Principal Investigator in preparing and submitting grant applications.
• Mentorship: Provide training and mentorship to postdocs, graduate students, and undergraduate students, fostering their research skills.

Minimum Qualifications

• Ph.D. or equivalent in Genetics, Molecular Biology, Cell Biology, Developmental Biology, Cancer Biology.
• Proven extensive experience in academic research, with a strong track record of publications.