Postdoctoral Fellowships in Cardiac and Neuronal Signal Transduction and Cardiac Physiology Research at Stanford University

Stanford University

Palo Alto, CA

ID: 7055045
Posted: January 2, 2019
Application Deadline: Open Until Filled

Job Description

There are open, fully-funded postdoctoral positions at Stanford University in the laboratory of Michael S. Kapiloff, MD, PhD, FAHA, a faculty member in the Departments of Ophthalmology and Cardiovascular Medicine and a member of the Stanford Cardiovascular Institute. We are seeking to recruit highly motivated cellular and molecular biologists with interests in cardiac or neuronal signal transduction. We are also seeking to recruit those with demonstrable in vivo experience in cardiac physiology (echocardiography and surgical models). Current research in the Kapiloff lab addresses how the formation of multimolecular protein complexes confers specificity in intracellular signaling and how these complexes are important for the function of cardiac myocytes in pathological remodeling and for the function of central nervous system neurons in stroke. A major focus of the lab has been the mAKAP scaffold protein that coordinates crosstalk between cAMP, calcium and MAP-kinase signaling pathways and that is important for the induction of pathological myocyte hypertrophy in the heart and for neurite extension and neuroprotection in the eye. Other projects include the study of novel scaffold proteins for the phosphatase calcineurin and for small GTPases. Research in the Kapiloff laboratory spans the breadth of signal transduction research from biochemistry to cell biology, including live cell imaging with FRET biosensors and in vivo animal physiology using genetically modified mouse models. In addition, basic research concepts studied in the laboratory are being applied to the development of novel gene therapy vectors for the treatment of heart failure and retinal diseases (glaucoma).

For more information, see the Kapiloff lab website at http://med.stanford.edu/kapilofflab.html

PhD must have been acquired no earlier than 2016. Strong English presentation and writing skills required. Record required of first author publication in the fields of biochemistry, molecular or cellular biology, pharmacology or physiology, published or accepted for publication into peer-reviewed journal.

Stanford is an equal opportunity employer and all qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.

Stanford post-doctoral fellow salaries are adjusted for living in the Bay area. See https://postdocs.stanford.edu/prospective-postdocs for more information.



 

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