ID: 7057779 (Ref.No. 308694JC)
Posted: June 14, 2019
Application Deadline: Open Until Filled
The Cytometry and Cell Sorting Core at Baylor College of Medicine is looking for a highly motivated individual to work with the core directors to help define and lead the Advanced Cytometry Unit. The position will be responsible for advanced multiparametric study coordination for the unit. This will include the organization of meetings between users, the bioinformatician, the technical specialists, and the antibody bank specialist. These meetings will be held to assist the users in selecting the most appropriate instrument for their goals, help them design the most effective antibody panels, establish the experimental protocol, and assist with data acquisition, analysis and interpretation. The position will also coordinate with staff in the Human Tissue Acquisition and Pathology Core for staining of tissue sections for the Hyperion and with staff within the Optical Imaging and Vital Microscopy Core for enhanced image analysis as needed. Finally, the position will be cross-trained for use of all multiparametric analyzers and antibody conjugation to better serve the users.
The Flow Cytometry Specialist II is a team-player who welcomes challenges. The position requires an advanced degree in Immunology, Oncology, or a related field and a minimum of three years of related experience. Experience with multiparametric cytometry and experience with large data-sets is preferred. The successful candidate will be responsible for supporting ongoing academic and preclinical research in immuno-oncology. The qualified individual will achieve this using high-dimensional in situ and in vitro techniques. The incumbent will also be responsible for advancing pipeline and new programs through studies to establish profiling datasets for mouse and human disease tissues.
- Establishes OMIPS relevant to institutional needs.
- Works with the Bioinformatics team at CCSC to develop and streamline analytical approaches for large flow and mass cytometry experiments.
- Works with CCSC users to design and implement larger flow and mass cytometry projects.
- Works with CCSC staff to operate and maintain our 29-color Symphony.
- Performs analysis of larger data-sets for CCSC users generated from flow and mass cytometry experiments.
- Collaborates with leaders in the fields of Immunology, Oncology and Cancer Biology including the members of the Dan L Duncan Cancer Center PI’s.
- Prepares data for publications and/or presentation.
- Prepares method sections and review result interpretation
- Works with other scientific staff members in writing research grant/contract applications for funding of research projects.
- Bachelor's degree in medical technology or a chemical, biological or physical science.
- Three years of flow cytometry experience in a laboratory environment. Education will not be substituted in lieu of experience.
- Flow cytometry and/or imaging
- Advanced Panel Design
- Client consultations
- Data Analysis
- Project Management
- Sample Prep
- Common immunological assays (cell activation, proliferation assays, cytokine analysis by FACS and ELISA, and multiplex assays)
- Independently designing and executing experiments, interpreting data
- Master's degree in a chemical, biological or physical science.
- Certification as a Laboratory Scientist or Medical Technologist.
- Mass cytometry
- Antigen Retrieval
- R programming
- Image analysis