Staff Scientist - Molecular and Human Genetics

Baylor College of Medicine

Houston, TX

ID: 7057889 (Ref.No. 308504KP)
Posted: June 14, 2019
Application Deadline: Open Until Filled

Job Description

The Aiden Lab is looking for a staff scientist to join our team.  The lab's work likes in the intersection of biology, computer science, physics and mathematics and its primary focus is exploring the three dimensional structure of the human genome. We are the 3D genome mapping center for the  ENCyclopedia of DNA Elements (ENCODE) Project  at the National Institutes of Health. Our lab is also a part of the National Science Foundation  Center for Theoretical Biological Physics , and a member of the  4D Nucleome Consortium .

A Staff Scientist conducts research under the general guidance of the principal investigator but exhibits the ability to plan and implement experiments and analyze their results. A Staff Scientist may have supervisory responsibilities for other laboratory personnel including the technical supervision of postdocs, students and technicians. This position will provide responsible and skilled technical assistance in support of a research project by completing assignments requiring a basic knowledge of fundamental techniques and practices related to molecular biology.

  • Designs, prepares and conducts laboratory research experiments (especially functional genomics experiments such as Hi-C, RNA-Seq, ChIP- Seq, ATAC-Seq).
  • Constructs and maintains new and existing mammalian cell lines (experience in mammalian cell culture is essential, experience with CRISPR and/or transposon-mediated integration, and fluorescence activated cell sorting [FACS] is useful).
  • Collects, compiles and analyzes data.
  • Performs HiC and other experimental studies as appropriate for the particular sample or project.
  • Assists with writing of grants or papers associated with the experiments completed.


  • Doctoral Degree. Experience may not be substituted in lieu of degree.
  • Three years of postdoctoral research experience. 
  • Experience in basic fundamental molecular biology techniques (such as gel electrophoresis, Western blotting, PCR, qPCR, molecular cloning)is essential. 
  • Experience in one or more of the following preferred: next generation sequencing library preparation; functional genomics (RNA-Seq, ChIP-Seq, ATAC-Seq); microscopy (especially fluorescence in situ hybridization [FISH]); RNAi; lentivirus production; biochemistry (protein purification from E. coli, baculovirus infected insect cells). 


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