ID: 7061897 (Ref.No. 10002334)
Posted: November 8, 2019
Application Deadline: Open Until Filled
City of Hope, an innovative biomedical research, treatment and educational institution with over 6,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.
Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.
This Project Development Scientist (Staff Scientist)position will be part of the Laboratory headed by Dr. Jianhua Yu, PhD and Michael Caligiuri, MD. This position will support scientific writing of grants, manuscripts, laboratory and clinical protocols. Direct report will be to Dr. Yu.
- Develop in-depth knowledge of basic and applied immunology: Scientists are expected to become well-versed in the terminology, biology and treatments associated with cancer and the immune system. The successful applicant will attend Immunotherapy Center Leadership meetings within the Hematologic Malignancies and Stem Cell Transplantation Institute (Heme Institute), Disease Team meetings for the relevant diseases (e.g., leukemia, myeloma, brain tumor), pre-clinical research data lab meetings, and relevant seminars and conferences to gain a thorough familiarity with the ongoing research interests of the Laboratory headed by Dr. Jianhua Yu, PhD and Michael Caligiuri, MD, as well as their collaborative research efforts across the City of Hope enterprise.
- Project Design and Grant Writing: The successful applicant will assist and advise researchers in the Yu and Caligiuri laboratory in design and preparation of new projects for funding as well as managing the logistics of grant submission, in coordination with the grant support team in the Heme Institute. They will help match investigators to appropriate grant opportunities throughout the stages of project and career development. They will edit/write the vast majority of the grant text and frame the project as appropriate for the specific application once a first draft is completed. They will design and finalize all figures. They will lead in preparing grant progress reports for grants that have been awarded.
- Laboratory and Clinical Protocol Writing and Submission: The successful applicant will work with the protocol design team (laboratory and clinical investigators, biostatisticians, research nurses, investigational pharmacists) on clinical trial design and protocol preparation for investigator-initiated early-phase clinical trials being performed by Drs. Yu and Caligiuri and their collaborators. The successful applicant will interface with Research Support Services to develop consent forms. For translational projects of Drs. Yu and Caligiuri involving a City of Hope-held Investigational New Drug Application (IND), they will provide and review text and figures for IND submission.
- Manuscript Writing and Public Access Compliance: The successful applicant will advise and assist investigators in the Yu and Caligiuri laboratory with interpretation and presentation of data for publication, and selection of appropriate journals for submission. They will edit/write portions of the manuscript text after a first draft is completed. S/he will also ensure that the appropriate funding agencies and the City of Hope Comprehensive Cancer Center Support Grant are acknowledged, and that NIH-funded manuscripts are archived in PubMed Central. S/he will become familiar with EndNote for the purposes of both manuscripts and grants, and maintain an Endnote master file.
- Data Presentations: Scientists will work with investigators to assure the clarity and accuracy of data presented, as well as the interpretation of results. They will contribute to the aesthetic aspects of data presentation, including formatting of text (to required specifications) and creation/refinement of clear, appealing data figures, graphics and treatment schemas, including PowerPoint presentations. This extends to meeting presentations, grants, protocols and manuscripts.
Basic education, experience and skills required for consideration:
- Preferred PhD in the biological/chemical sciences; or, a master's degree with at least five years or bachelor's with 10 years, of scientific writing, clinical study design, or clinical trial regulatory experience in a healthcare/research/academic environment.
- Excellent scientific writing, organizational and interpersonal skills are key.
- Ability to work independently and as part of a team, meet deadlines, perform and prioritize multiple simultaneous tasks. Requires judgment that could affect the image of City of Hope and the Institute.
- Proficiency in use of Microsoft Word, EndNote, Excel and PowerPoint. Prefer familiarity with Adobe Acrobat and Illustrator.
- Strong written and verbal English is required.
- NIH or DOD research grant writing (R01 level, not post-doctoral fellowships), involvement with human observational or therapeutic studies, protocol design/writing for human sample, observational/retrospective or therapeutic studies. Familiarity with data analysis techniques, graphing methods, and interpretation of laboratory and clinical data.
- For more information about Drs Yu and Caligiuri, please visit: https://www.cityofhope.org/faculty/jianhua-yu and https://www.cityofhope.org/michael-caligiuri/.