Staff Scientist - Leader, Correlative Studies for CAR T Cell Clinical Trials

City of Hope

Duarte, CA

ID: 7061913 (Ref.No. 15196-TBE)
Posted: November 16, 2019
Application Deadline: Open Until Filled

Job Description

About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 6,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary

The T Cell Immunotherapy Program at City of Hope is a fast-paced laboratory involved in cutting-edge technology, research and clinical immunotherapy studies. We are currently looking for a staff scientist who will lead a correlative studies team for our CAR T cell clinical trials in brain tumors.

Key Responsibilities:

  • The PhD candidate will ideally have considerable experience in the fields of immunology, immunotherapy and cancer/brain tumor biology.
  • Expertise in handling of high-dimensional analysis of primary tissues, including multiparameter flow cytometry, immunohistochemistry and/or gene expression profiling is highly preferred.
  • This position will interact and collaborate with a team of researchers focused on developing T cell therapies in a translational research environment.

Follow established City of Hope and department policies, procedures, objectives, performance improvement, attendance, safety, environmental, and infection control guidelines, including adherence to the workplace Code of Conduct and Compliance Plan.

Practices a high level of integrity and honesty in maintaining confidentiality

Performs other related duties as assigned or requested.

Basic education, experience and skills required for consideration:

  • Ph.D degree with research experience in the fields of immunology immunotherapy and cancer/brain tumor biology.
  • Ability to effectively lead a research team to successfully meet project goals.
  • Ability to collaborate with diverse group of scientists involved in the correlative studies.
  • Ability to design and execute laboratory experiments, critically interpret experimental results, and present data in a clear and concise manner.
  • Ability to apply/use bioinformatics for analyses and interpretation of RNA-Seq and Single Cell RNA-Seq data is highly preferred.
  • Ability to participate in the preparation of grant applications and scientific publications.
  • Excellent oral and written communication skills.

Preferred Experience:

  • A publication record in peer-reviewed scientific journals.
  • Immunology expertise, prior postdoc experience, with cell biology and animal work.
  • T cell therapy and/or oncolytic virus experience, a big plus.

Additional Information:
See the Christine Brown, Ph.D. or Stephen Forman, M.D. web page for an overview of research interests at:,,

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.


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