Postdoctoral Fellow - Genome Editing for Hemophilia

City of Hope

Duarte, CA

ID: 7070570 (Ref.No. 10007811)
Posted: October 3, 2020
Application Deadline: Open Until Filled

Job Description

About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation’s leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary
The Beckman Research Institute of City of Hope is looking for exceptional Postdoctoral Fellows for translational research projects utilizing a non-nuclease genome editing platform. Exciting cutting-edge projects will focus on studying mechanisms of action, approaches to defining genomic, structural and functional characteristics of novel genetic vectors, novel therapeutic strategies and validation in in-vivo models of human disease. Experience with homologous recombination, chromatin immunoprecipitation, protein-protein and protein-DNA interactions, next generation sequencing, computational analyses, cell culture models and in-vivo models is desirable. A strong background in molecular virology and biology is helpful. Motivated, industrious, rigorous, independent yet collaborative individuals with outstanding communication skills will be ideally suited for these positions.

Key Responsibilities:
  • Design and execute experiments within project
  • Take responsibility for different aspects of assigned project
  • Analyze data and present results
  • Interface collaboratively with other lab members
  • Experimental work includes some or all the following: molecular biology, PCR, cloning, sequencing, RNA and DNA analysis, tissue culture, primary cell culture, in vivo imaging, in vivo disease models.

Basic education, experience and skills required for consideration:
  • A Ph.D. degree in life or biomedical sciences, or a related discipline is required.
  • Strong background in molecular biology is required.
  • Experience with molecular virology, bioinformatics and genetics is desirable.
Additional Information:
  • For more information on Dr. Saswati Chatterjee’s research please visit, here .
City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.


City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.


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