Postdoctoral Position in Developmental Cell Biology

University of Texas Southwestern Medical Center

Dallas, TX

ID: 7071697
Posted: November 2, 2020
Application Deadline: Open Until Filled

Job Description

Postdoctoral fellow position, Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas

A postdoctoral fellow position is available in the laboratory of Professor Elizabeth Chen to study the molecular and cellular mechanisms of cell-cell fusion in development and regeneration. Cell-cell fusion is critical for fertilization, muscle development, bone remodeling, immune response, placental formation, and stem cell-mediated tissue regeneration. Failure in cell fusion leads to a plethora of defects such as infertility, congenital myopathy, osteopetrosis, immune deficiency, and preterm birth.

The Chen lab (https://www.utsouthwestern.edu/labs/chen-elizabeth/) discovered the asymmetric fusogenic synapse, as well as actin polymerization- and actomyosin-mediated mechanical interactions between fusing cells [Science 340,359-63; Dev Cell 32,561-73; Nat Cell Biol 20,688-698; Nat Cell Biol 22,674-688].

Current research in the Chen lab is conducted using a multidisciplinary approach (involving genetics, molecular biology, cell biology, biochemistry and biophysics) in multiple experimental systems (Drosophila, zebrafish, mouse and cultured cells). The postdoctoral fellow will work on an NIH-funded project in a dynamic, versatile and collaborative lab environment. Research areas include cell-cell fusion, actin cytoskeleton, mechanobiology, membrane biology, and muscle biology.

Requirements

We are looking for a creative and motivated young investigator with a doctoral degree and a strong background in genetics, cell biology, molecular biology, biochemistry and/or biophysics. Prior experience with Drosophila genetics is preferred but not required.

To apply

Interested candidates should send CV and three letters of reference to Dr. Elizabeth Chen (Elizabeth.Chen@UTSouthwestern.edu).

Departments of Molecular Biology
UT Southwestern Medical Center
6000 Harry Hines Blvd.
NA8.102
Dallas, TX 75390

UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. In accordance with federal and state law, the University prohibits unlawful discrimination, including harassment, on the basis of: race; color; religion; national origin; sex; including sexual harassment; age; disability; genetic information; citizenship status; and protected veteran status. In addition, it is UT Southwestern policy to prohibit discrimination on the basis of sexual orientation, gender identity, or gender expression.




 

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