Research Technician in Structural Molecular Biology

University of Leeds

Leeds, United Kingdom

ID: 7073866 (Ref.No. FBSFO1145)
Posted: January 8, 2021

Job Description

Are you an early career researcher looking for a challenge?  Do you have a background in Structural Molecular Biology?  Do you want to further your career in one of the UK’s leading research intensive Universities?

This post is funded by a British Heart Foundation Intermediate Fellow awarded to Dr Charlotte Scarff to study the structural basis of hypertrophic cardiomyopathy, an inherited heart disease, caused by mutations in heart muscle proteins.

This is a 2-year fixed term post (with the potential for extension), in which you will work with Dr Scarff and members of her research team to support projects investigating the structure, function and interactions of key heart muscle proteins with the aim of understanding why specific mutations result in disease. You will use a combination of approaches that will include expression and purification of proteins in E.coli, insect and mammalian cells, mammalian cell culture and protein characterisation approaches. You might also be asked to help prepare samples for electron microscopy, mass spectrometry, circular dichroism or protein-protein interaction experiments. You should have a Degree, BTEC higher level or equivalent, or equivalent experience in structural molecular biology or a related discipline, with experience of working in a laboratory environment, using standard routine molecular biology techniques, and experience in the expression and purification of proteins in bacteria, and insect and/or mammalian cells.

The University of Leeds and the Faculty of Biological Sciences are committed to providing equal opportunities for all and offer a range of family friendly policies. The University is a charter member of Athena SWAN (the national body that promotes gender equality in higher education), and the Faculty of Biological Sciences was awarded a Silver award in 2020.  We are proud to be an inclusive Faculty that values all staff, and are happy to consider job share applications and requests for flexible working arrangements from our employees. Our Athena SWAN webpage provides more information. 

To explore the post further or for any queries you may have, please contact: 

 Dr Charlotte Scarff, BHF Intermediate Fellow

Tel: +44 (0)113 343 4370, Email:


Carsten Zothner, Laboratory Area Coordinator

Tel: +44 (0)113 343 3087, Email:

Location:  Leeds - Main Campus
Faculty/Service:  Faculty of Biological Sciences
School/Institute:  Biological Sciences Faculty Offices
Category:  Technical Support
Grade:  Grade 5
Salary:  £23,067 to £26,715 p.a.
Working Time:  35 hours per week
Post Type:  Full Time
Contract Type:  Fixed Term (2 years)
Release Date:  Wednesday 06 January 2021
Closing Date:  Friday 05 February 2021
Reference:  FBSFO1145

The University community is made up of a wide range of people with diverse backgrounds and circumstances, which we value and regard as a great asset. As part of our continued commitment to equality and inclusion, we strive to create an environment where everyone can reach their full potential and have a real opportunity to participate in and contribute to our activities.


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