Postdoc Positions on Study of Neurodegenerative Disease

Case Western Reserve University

Cleveland, OH

ID: 7074474
Posted: January 26, 2021

Job Description

Two postdoc positions are immediately available in the laboratory of Dr. Xin Qi in the Department of Physiology & Biophysics at Case Western Reserve University School of Medicine.

The lab focuses on mitochondrial pathology in neurodegenerative diseases, including Alzheimer’s, Parkinson’s, and Huntington’s disease. We use a combination of in vitro cell culture, in vivo transgenic animal models, and patient-derived neurons to study the mechanisms by which mitochondrial quality control impairment contributes to neurodegeneration. Another research focus of the lab is the development of therapeutics that enhance mitochondrial function to treat human diseases. We have been using the rationally designed peptide inhibitors of protein-protein interactions and high throughput screening to identify mitochondrial functional enhancers as therapeutic options.

The successful applicants will participate in NIH-funded projects on elucidating the molecular basis of mitochondrial damage and metabolic dysregulation in neurodegenerative diseases. The applicants must have a Ph.D. and/or MD degree in neuroscience, molecular biology, cell biology, pharmacology, or related field. Candidates with experience in neurodegenerative diseases and transgenic mouse models are highly desired.

Interested individuals should send a cover letter, CV, and the names/phone numbers of three people who could provide letters of reference by email to Xin Qi, Ph.D., Please visit our lab website at for additional information.


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