Postdoctoral Fellow position: neuroimmune mechanisms of depression comorbid with chronic pain

The University of Texas MD Anderson Cancer Center

Houston, TX

ID: 7075330
Posted: February 20, 2021
Application Deadline: Open Until Filled

Job Description

The Grace lab is seeking an enthusiastic Postdoctoral Researcher to study how brain glia contribute to affective and cognitive disturbances that are co-morbid with high-impact chronic pain. This project involves complex behavioral measures of depression and motivation in models of neuropathic pain, stereotaxic surgeries, transgenic mouse strains, super-resolution microscopy, single-cell and next-generation RNA sequencing, and other biochemical techniques.

The applicant will join the Laboratories of Neuroimmunology, consisting of the research teams of five collaborating Principal Investigators who aim at understanding chronic pain, cognitive deficits and fatigue in response to cancer and its treatment. The post-doctoral fellow will work under direct supervision of the Principal Investigator.

We highly value innovation, learning, hard work, creativity and an interactive, respectful and fun atmosphere. If you are interested in helping to understand the molecular and cellular mechanisms of pain and developing novel interventions to help improve the quality of life for people suffering from chronic pain in an internationally-renowned, well-funded group of scientists using a highly integrated and interdisciplinary approach in the number one cancer center in the USA, we are the perfect environment for you!

A PhD in neuroscience, immunology, or related disciplines is required. Experience in working with rodents and a background in pain or immunology is preferred.


ESSENTIAL FUNCTIONS

1. Research Activity
• Nerve injury and stereotaxic surgeries in mice
• Behavioral measures of pain, and affective and cognitive disturbances in mice
• Immunohistochemistry and microscopy studies on cells and nervous system tissues
• Single-cell and bulk RNA-seq
• Western blotting and qPCR
• Luciferase assays and immunoassays
• Collect and process ex vivo biological samples including brain and spinal cord
• Present results in departmental and national meetings
• Prepare and write manuscripts for publication.

2. Interpersonal Skills, Communication, Learning Skills
• Strong written and oral communication skills
• Communication with faculty and staff within and outside the laboratory.
• Ability to work with others in a highly collaborative manner.
• Good problem-solving abilities.

3. Other
• Responsible for monitoring laboratory equipment and implementing safety procedures.
• Strong interest in basic and translational research
• Supervision of 1-2 research assistants

For further information you should contact Birute Ziemiene (bziemiene@mdanderson.org).


Diversity and inclusion at MD Anderson are not just important; they are essential. We take an expansive view of diversity, considering differences in race, ethnicity, sexual orientation, gender and religious beliefs, as well as communication styles, thought, skill and ambition. We constantly examine our culture to create an inclusive working environment that effectively attracts, retains, develops and utilizes the skills and talents of all employees. Our Diversity Council develops strategies to attract and retain superior talent and enhance workforce diversity and inclusion. We also offer multiple diversity training programs to our employees.



 

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