Postdoctoral Fellow - Leukemia (Battula)

The University of Texas MD Anderson Cancer Center, Leukemia Department

Houston, TX

ID: 7077639
Posted: April 26, 2021
Application Deadline: Open Until Filled

Job Description

Position/Program Description:
A postdoctoral research fellowship position is available to study breast cancer stem cells. The laboratory is studying ganglioside GD2 and GD3 synthase in the regulation of cancer stem cell function in triple-negative breast cancer. In particular, we are interested in developing novel small molecule inhibitors for targeting GD3 synthase in breast cancer cells as a part of DoD funded project. Postdoctoral fellows are responsible for developing GD3 synthase inhibitors using several molecular and computational approaches and testing the compounds in vitro stem cell assays and in vivo tumor growth studies. Candidates must have a doctoral degree with 0-2 years of postdoctoral experience. Preference will be given to candidates with previous experience with protein modeling, drug discovery/development, computational tools, mouse models, cancer stem cell biology, basic cell culture, and imaging skills. Candidates are expected to be self-motivated and have excellent writing and communication skills.

Learning Objectives:
The potential candidate is expected to quickly learn various tissue culture techniques, stem cell functional assays, metabolic assays that we routinely use in our laboratory. Also, we have several animal models, including patient-derived xenografts, that need to be maintained and used for translational research. A thorough understanding of cancer biology, drug development, molecular modeling is appreciated.

Eligibility Requirements:
Ph.D. degree in life science (cellular or molecular biology). Research experience and an excellent knowledge base in biochemical, metabolic, and signaling processes related to cancer. Experience in breast cancer, molecular cloning, the quantitative measurement of RNA expression, flow cytometry, protein modeling, big data analysis, and/or the use of animal models would be a plus. The applicant should enjoy providing a training role for students and other coworkers and should be open to scientific collaboration within the institution and outside the institution. The candidate should possess excellent written and spoken (English) communication skills and should be able to present scientific data at international meetings.

Interested applicants should send a Cover Letter detailing past research experience/skills/accomplishments.
Please submit a current Curriculum Vitae including the contact information of three (3) Referees to Dr. Venkata Lokesh Battula with the subject line entitled “Postdoctoral Fellow - Application – Applicant’s Name” to

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