Research Fellow in Molecular Virology

University of Leeds

Leeds, United Kingdom

ID: 7079492 (Ref.No. FBSMB1192)
Posted: June 7, 2021

Job Description

Are you an ambitious researcher looking for your next challenge?  Do you have an established  background in Molecular Virology.  Do you want to further your career in one of the UK’s leading research intensive Universities?

Project Title: Assessing Kaposi’s sarcoma-associated herpesvirus-host cell interactions (Maternity Cover)

Human herpesviruses are responsible for a range of debilitating acute and chronic infections, in addition some members are associated with human cancers. Conventional anti-herpesvirus therapy has been effective for many years, however the emergence of drug-resistant strains and the lack of effective antivirals or vaccines for the oncogenic herpesviruses necessitates the continued development of anti-herpesvirus strategies and reagents.

We are seeking a highly motivated research fellow to investigate how the human tumour virus, Kaposi’s sarcoma-associated herpesvirus (KSHV), manipulates host cell non-coding RNAs to enhance its own replication. The post will be based in the Whitehouse research group, Leeds. The project will use a range of molecular and genomic-based approaches to highlight a novel KSHV-mediated mechanism to regulate viral gene expression. Moreover, this project aims to identify a novel targets for antiviral intervention for this important human tumour virus.

You should have a PhD (or close to completion) in Molecular Virology, Cell Biology or a closely allied discipline, with excellent communication skills, evidence of a good publication track record, and experience in growth, analysis and manipulation of Kaposi’s sarcoma-associated herpesvirus. You will join a highly active research group studying various aspects of human tumour virus biology and will become part of a multi-member laboratory team investigating the molecular mechanisms of viral infection and the essential role of virus-host cell events. These are fundamentally important to ultimately develop new effective antiviral agents that target viral proteins or host factors.

To explore the post further or for any queries you may have, please contact:

Professor Ade Whitehouse

Tel: +44 (0)113 343 7096, email: a.whitehouse@leeds.ac.uk             

Location:  Leeds - Main Campus
Faculty/Service:  Faculty of Biological Sciences
School/Institute:  School of Molecular & Cellular Biology
Category:  Research
Grade:  Grade 7
Salary:  £33,797 to £40,322 p.a.
Due to funding limitations it is unlikely an appointment will be made above £33,797
Post Type:  Full Time
Contract Type:  Fixed Term (Available from 1 August 2021 on a fixed term basis for 12 months)
Release Date:  Saturday 05 June 2021
Closing Date:  Saturday 19 June 2021
Reference:  FBSMB1192


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