Staff Scientist- Translational Immunotherapy

Harvard Medical School

Boston, MA

ID: 7086021
Posted: September 23, 2021
Application Deadline: Open Until Filled

Job Description

Job Summary

The Wyss Institute is seeking a highly motivated and innovative Scientist with expertise in Immuno-materials, Immunology and Immunotherapy to join a dynamic team dedicated to the discovery, development, and translation of novel immune-therapies for the treatment of disease. For more information regarding our Immuno-materials technologies, please visit: https://wyss.harvard.edu/technologies/?taxonomy=focus_area&term=612



About Us:

The Wyss Institute for Biologically Inspired Engineering at Harvard University is not a typical research organization as our goal is near-term impact. Our mission is to transform healthcare and the environment by emulating the way nature builds, and getting our innovations out of the lab and into the real world, fast. At the Wyss Institute, faculty from premier academic and clinical institutions collaborate with staff scientists and engineers, postdocs, graduate students, industry experts, business development leaders, and entrepreneurs across disciplines to produce new technologies that don’t just succeed at making it to the market – they disrupt it. We support research that universities, companies, and VC firms don’t fund because they claim it’s too risky. We prefer to use the word “challenging,” and we love challenges. For more information, visit: http://wyss.harvard.edu/



About You:

You are a collaborative, impact-focused problem solver who wants to be part of a dynamic team dedicated to creating and commercializing novel approaches to global challenges in healthcare and sustainability. You want the freedom to explore, to push the boundaries of what is possible, to use your ambition to tackle challenging projects in a fast-paced, industry-focused environment without a lot of administrative hurdles. As an entrepreneurially-minded individual with an outgoing personality, you will combine your experience in biomaterials and immunotherapies with product development goals and applications in biology and medicine, and you will excel at the opportunity to foster wide-ranging scientific collaborations with some of the world’s leading scientists, engineers, students, and fellows. You enjoy working with diverse groups of people and leveraging your own expertise to create innovations that can change the world.



About the role:

We are looking for an innovative scientist with experience working with the modulation of T Cell and Dendritic Cell function in cancer, autoimmune, and/or other disease models. Familiarity with in vivo and in vitro models of innate and adaptive immune responses, flow cytometric characterization and separation of various immune cell populations, and biomarkers or imaging modalities relevant to immunological endpoints is essential. Reporting to the Lead Staff Scientist, and in collaboration with Core Faculty Member, David Mooney, you will develop and conduct functional assays and utilize models to validate the biological properties and therapeutic potential of Immunotherapy treatments. As a part of our Advanced Technology Team, you will be exposed to many different technologies in areas ranging from therapeutics and diagnostics to synthetic biology and materials science, with the goal to identify new product solutions and the unique opportunity to follow your passion either at the Institute or as a future co-founder of a Wyss start-up.


Job-Specific Responsibilities

What you'll do:

Support external collaboration opportunities with the business development team
Plan, conduct and interpret studies with various animal and cell culture models that utilize functional assays to validate the biological properties and therapeutic potential of Immunotherapy treatments
Collaborate with material scientists to develop material-based immunotherapies
Support and contribute to the writing of research proposals and reports to funding agencies, providing critical data, figures, or information for grant and patent submissions
Assist faculty and other researchers on manuscripts, abstracts, and other publications of research findings
Ensure detailed and technology transfer ready documentation and institutional memory for product development projects in the form of reports and SOPS
Mentor and train others on research methodology
Present research results at Wyss internal and external meetings
Demonstrate a commitment to diversity, inclusion, and cultural awareness through actions, interactions, and communications with others

Basic Qualifications

What you'll need:

Bachelor’s degree in Immunology, Immunotherapy, Cell Biology, or another related field required.
A minimum of 4 years of experience with in vivo and in vitro promotion, inhibition, and detection of immune cells, including dendritic cells, cytotoxic T cells, and antigen presentation and co- stimulation or related areas; an Advanced Degree may count towards years of experience.

Additional Qualifications and Skills

Desirable Skills:

Ph.D. is strongly preferred.
Demonstrated broad theoretical and practical knowledge in at least one of the following fields: Immunology, Cancer Biology, Infectious Disease, or Autoimmunity.
Product development-oriented experience, in either an industry or academic setting preferred.
Demonstrated success in leading and working in cross-functional teams.
Excellent documentation, analytical, communication, and interpersonal skills.
Comfortable in a fast-paced translational environment and able to adjust scientific approach based upon changing priorities.
The ability to seek out collaborations, and manage and mentor others.

Working Conditions

This position will be based on our campus in Boston, MA and will require on-campus presence. Subject to business needs, the Wyss Institute generally supports flexible work arrangements.

Harvard Medical School strives to cultivate an environment that promotes inclusiveness and collaboration among students, faculty and staff and to create new avenues for discussion that will advance our shared mission to improve the health of people throughout the world.