Postdoctoral Fellow – Rapid Manufacturing of Regenerative Heart Valves

The Wyss Institute for Biologically Inspired Engineering at Harvard University

Boston, MA

ID: 7087088
Posted: October 13, 2021
Application Deadline: Open Until Filled

Job Description

About the Wyss:

The mission of the Wyss Institute for Biologically Inspired Engineering at Harvard University is to transform human healthcare and the environment by emulating the way nature builds. Developed as an alliance between Harvard and other premier academic and clinical partner institutions, Institute faculty and staff collaborate in high-risk, fundamental research and science-driven technology development. A major focus of the Institute is to translate the technologies developed by its faculty and staff into commercial products and therapies through collaborations with clinical investigators and establishment of corporate alliances.

Role Description:

Kevin Kit Parker’s Disease Biophysics Group at the Harvard University’s Wyss Institute for Biologically Inspired Engineering seeks a talented post-doctoral fellow to work on the rapid manufacturing of regenerative heart valves, or JetValves. The candidate will use the proprietary rotary jet spinning technologies developed in the Parker lab to design, build, and test heart valve replacements using natural and synthetic polymeric nanofibers. The goal of this translational project – which is part of an international collaboration with the University of Zurich in Switzerland – is to complete the preclinical characterization of JetValves in preparation for a first-in-man clinical trial.

In This Role You Will:

Working together with a team of engineers, chemists, and applied mechanicians, the candidate will be responsible for nanofiber production and valve manufacturing, quality assessment, and structural and functional validation in vitro
Perform standards tests using methodologies such as Instron®, FTIR, SEM, microCT, pulse duplicator testing, and cell infiltration
Participate in the in vivo and post-mortem validation of JetValves implanted in sheep, including analysis of explanted samples via SEM and immunohistochemistry.

What You’ll need:

Ph.D. in cardiovascular tissue engineering or related fields
Expertise with in vitro and/or in vivo characterization of heart valves or heart valve replacements
Background in Materials Science and proven experience with nanofiber fabrication (e.g., electrospinning) or additive manufacturing methodologies (e.g., 3D printing) will be positively evaluated

Benefits and Perks:

Medical/Dental/Vision: We offer a variety of excellent medical, dental, & vision plans. All coverage begins as of your start date.
Time Off: 20 days of vacation per year
Tuition Assistance Program: Competitive tuition assistance program, classes at the Harvard Extension School and discounted options through participating Harvard grad schools.
Transportation: Harvard offers a 50% discounted MBTA pass as well as additional options to assist employees in their daily commute.
Wellness Options: Harvard offers programs and classes at little or no cost, including stress management, nutrition, meditation, and complimentary health services.

Where You Can Apply:

Interested candidates should submit their application packet to Prof. Kevin Kit Parker ( and his admin assistant Kelly Rush ( as a single pdf file with the following documents: cover letter, CV, 3 relevant first author paper(s), and the names of three referees.


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