Bioinformatics Postdoctoral Appointee

Sandia National Laboratories

Livermore, CA

ID: 7088300 (Ref.No. 679183)
Posted: November 3, 2021

Job Description

This postdoctoral position is a temporary position for up to one year, which may be renewed at Sandia's discretion up to five additional years. The PhD must have been conferred within five years prior to employment. Individuals in postdoctoral positions may bid on regular Sandia positions as internal candidates, and in some cases may be converted to regular career positions during their term if warranted by ongoing operational needs, continuing availability of funds, and satisfactory job performance. Employees must remain in their current position for one year before applying for a new position, with the exception of student interns. Application of this requirement will not supersede collective bargaining agreements. See collective bargaining labor agreements for represented bidder eligibility requirements for represented employees. : This posting will be open for application submissions for a minimum of seven (7) calendar days, including the ‘posting date’. Sandia reserves the right to extend the posting date at any time. : Sandia demonstrates its commitment to public safety in the national interest by requiring that all new hires attest to their vaccination status before commencing employment. The requirement also applies to those who are telecommuting and working virtually. Any concerns about the ability to meet this requirement should be directed to HR Solutions at (505) 284-4700. : Are you looking to do creative research that addresses civilizations’ major challenges such as climate change and infectious disease? Would you be excited to work as part of a hard working, multidisciplinary team, interacting with outstanding scientists across multiple national labs and universities? Sandia/California’s Systems Biology Department is seeking dedicated bioinformaticians/computational biologists to join our research team. The selected applicant will engage in fundamental work improving the characterization of mobile elements and horizontal gene transfer across the bacterial kingdom, and help develop applied technologies derived from this knowledge base such as new synthetic biology and gene editing methods and vectors, and advanced phage therapy. On any given day, you may be called on to: + Devise innovative computational approaches to expand and annotate the world’s largest well-curated database of microbial genomic islands + Work with experimental colleagues to design, model and analyze high-throughput screens and advanced synthetic biology constructs + Mentor technologists and interns + Work collaboratively to implement, maintain, and refine project plans with an integrated multidisciplinary team that may include members from national labs, universities and industry + Communicate your research through writing scientific papers, publishing in peer-reviewed journals, and communicating findings at seminars and conferences + Contribute to the creation and development of new scientific research proposals

+ PhD in bioinformatics or computational biology, or, in biochemistry, microbiology, evolutionary biology or a related field coupled with strong experience in bioinformatics or computational biology. Alternatively, a PhD in computer or information sciences with an academic foundation in biology and strong interest in developing bioinformatics skills. + Familiarity with prokaryotic genomics, genetics and molecular biology + Proven record of high technical accomplishment and written communication (e.g. as evidenced by publication in high-impact scientific journals) and strong verbal communication and data presentation skills (e.g., as demonstrated through scientific conference presentations)

+ Strong background in microbiology, including studies of microbiomes, microbial communities and bacterial or archaeal viruses + Bioinformatics skills and familiarity with related software tools for phylogenetics, comparative genomics, genome assembly and genome annotation + Strong background in statistics, machine learning and data science with applications to biological data analysis (e.g., from next-generations sequencing or high-throughput screening methods) + Proven programming and database skills (e.g., python, Perl, C++, MySQL) + Experience with genome engineering and synthetic biology or with high-throughput functional genomics screens (e.g., CRISPR or transposon based) + Computational biology skills and experience with protein engineering, phage display or directed evolution method

Department Description:

The Systems Biology Department, located in Livermore, California is a diverse research group with a focus on both basic and applied biological research. We seek to address problems with strong ties to national security, including as biodefense and health security, and climate and energy security. We do this using innovative research approaches in microbiology, virology, synthetic biology, immunology and bioinformatics, incorporating advanced technology development including CRISPR/Cas technologies, advanced omics, and advanced materials and nanotechnology. We also seek to develop the science-based needed to produce clean, efficient, and cost-effective biofuels and other bioproducts on a commercial scale. Our department the highly multidisciplinary Applied Biosciences and Engineering Group, comprised of researchers with expertise in many fields of biology (molecular biology, microbiology, virology, immunology and biochemistry), chemistry (analytical, organic and physical), computational science (bioinformatics, machine learning, computational chemistry), and engineering(chemical, mechanical and biomedical).

About Sandia:

Sandia National Laboratories is the nation’s premier science and engineering lab for national security and technology innovation, with teams of specialists focused on cutting-edge work in a broad array of areas. Some of the main reasons we love our jobs:• Challenging work with amazing impact that contributes to security, peace, and freedom worldwide• Extraordinary co-workers• Some of the best tools, equipment, and research facilities in the world• Career advancement and enrichment opportunities• Flexible work arrangements for many positions include 9/80 (work 80 hours every two weeks, with every other Friday off) and 4/10 (work 4 ten-hour days each week) compressed workweeks, part-time work, and telecommuting (a mix of onsite work and working from home)• Generous vacations, strong medical and other benefits, competitive 401k, learning opportunities, relocation assistance and amenities aimed at creating a solid work/life balance* World-changing technologies. Life-changing careers. Learn more about Sandia at:*These benefits vary by job classification.

Security Clearance:

This position does not currently require a Department of Energy (DOE) security clearance. Sandia will conduct a pre-employment drug test and background review that includes checks of personal references, credit, law enforcement records, and employment/education verifications. Furthermore, employees in New Mexico need to pass a U.S. Air Force background screen for access to Kirtland Air Force Base. Substance abuse or illegal drug use, falsification of information, criminal activity, serious misconduct or other indicators of untrustworthiness can cause access to be denied or terminated, resulting in the inability to perform the duties assigned and subsequent termination of employment. If hired without a clearance and it subsequently becomes necessary to obtain and maintain one for the position, or you bid on positions that require a clearance, a pre-processing background review may be conducted prior to a required federal background investigation. Applicants for a DOE security clearance need to be U.S. citizens. If you hold more than one citizenship (i.e., of the U.S. and another country), your ability to obtain a security clearance may be impacted. Members of the workforce (MOWs) hired at Sandia who require uncleared access for greater than 179 days during their employment, are required to go through the Uncleared Personal Identity Verification (UPIV) process. Access includes physical and/or cyber (logical) access, as well as remote access to any NNSA information technology (IT) systems. UPIV requirements are not applicable to individuals who require a DOE personnel security clearance for the performance of their SNL employment or to foreign nationals. The UPIV process will include the completion of a USAccess Enrollment, SF-85 (Questionnaire for Non-Sensitive Positions) and OF-306 (Declaration of for Federal Employment). An unfavorable UPIV determination will result in immediate retrieval of the SNL issued badge, removal of cyber (logical) access and/or removal from SNL subcontract. All MOWs may appeal the unfavorable UPIV determination to DOE/NNSA immediately. If the appeal is unsuccessful, the MOW may try to go through the UPIV process one year after the decision date.

EEO Statement:

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, or veteran status and any other protected class under state or federal law.

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status.