Research Associate II - Translational Research and Cellular Therapeutics

City of Hope

Duarte, CA

ID: 7097925 (Ref.No. 10016298)
Posted: July 4, 2022
Application Deadline: Open Until Filled

Job Description

About City of Hope

City of Hope is an independent biomedical research and treatment organization for cancer, diabetes and other life-threatening diseases.

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution.  AccessHope™, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hope’s specialized cancer expertise.

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

City of Hope’s commitment to Diversity, Equity and Inclusion

We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all of our communities.  Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds and experiences to our work -- and that our teams align with the people we serve in order to build trust and understanding.  We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds and perspectives; this is reflected in our work and represented in our people.

Position Summary

Under general supervision of the Principal Investigator, or designee, the Research Associate directs the work of a laboratory or undertakes research projects in collaboration with academic supervisor, making innovative contributions pertaining to laboratory procedures and lab research. RA typically consults with the academic supervisor or designee, on the scope and plan of approach to a research project; reads abstracts and articles; organizes and plans techniques; assists other lab members in their projects; contributes original ideas to the laboratory research; standardizes new techniques and trains staff on these techniques; performs specialized procedures and prepares written reports of laboratory experimental methods. This lab position requires training in molecular and cellular biology with an emphasis on metabolic diseases such as obesity and diabetes. Specific techniques that will be commonly used include tissue culture, isolation of RNA, DNA, and protein, RT-PCR, western blotting, basic mouse phenotyping (metabolic parameters and tissue collection), DNA extraction, PCR analysis, histological techniques, fluorescent microscopy, computer skills (word processing, email, spreadsheet management, adobe photoshop, Image J), and lab organization skills (organizing safety information and training, inventory management, ordering supplies and record keeping).  

Key Responsibilities include:

  • Performs a variety of routine and non-routine laboratory research experiments. Records and validates results for accuracy and completeness.
  • Troubleshoots procedures if experiment results are unexpected or unsatisfactory. Recommends alternative procedures.
  • Responsible for accurately recording work performed including results and methodology.  Calculates, compiles and analyzes data obtained from work performed.
  • Responsible for overall lab maintenance including ordering, organization, maintenance of lab equipment, and chemical waste management, under guidance of lab members.
  • After the training period should independently evaluate research data and initiate alternative approaches to improve the quality of results by providing input to overall research design. Trains lab staff in specialized procedures, equipment and theoretical concepts behind unique tests.
  • May contribute to the preparation of manuscripts by describing methods and specialized techniques.  Keeps abreast of new and improved techniques.
  • Ensures that all laboratory activities are carried out in compliance with each procedure(s) by utilizing safety procedures and guidelines in handling, storage and disposal of bio-hazardous, infectious and toxic material.

Basic education, experience and skills required for consideration:

  • Bachelor’s degree or Master’s degree.
  • Two years related research/ laboratory experience with a Bachelor’s degree

or one year related research/ laboratory experience with a Master’s degree.

Preferred education experience and skills:

  • Master’s degree preferred.
  • Prefer lab research experience during or after undergraduate training.

Additional Information:

  • As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer.  All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.



City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.