Postdoctoral Fellow - Genomic Medicine Department
Posted: June 21, 2022
Application Deadline: Open Until Filled
Job DescriptionA Postdoctoral position is available in the Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. This position reports to Robert Tyler Hillman, MD, PhD in Genomic Medicine Department.
We seek a talented and highly motivated Postdoctoral Fellow to perform hands-on experiments performing in vitro and in vivo experiments to characterize the function and efficacy of a novel kinase inhibitor in the treatment of ovarian granulosa cell cancer. This is a rare cancer type with few effective treatment options, and this project will be crucial for the pre-clinical evaluation of a promising novel therapeutic. Opportunities also exist to design and conduct high-throughput drug screening assays using tumor model systems developed in the lab. These model systems include isogenic cell lines generated in the lab using CRISPR/Cas9 genome editing, as well as 3D tumor organoid models derived from primary tumor tissue. The fellow will gain experience in the maintenance and propagation of ovarian cancer organoids, as well as their use in drug treatment studies. The fellow will also be involved in translational study design, data analysis and manuscript preparation by attending lab meetings, journal clubs, and research seminars. The Hillman lab is a wet/dry hybrid lab with multidisciplinary projects that span a wide range of experimental techniques and gynecologic cancer histologies. It is a vibrant environment with numerous opportunities for acquiring new experimental or computational skillsets.
The primary research focus is to characterize the efficacy and mechanism of a novel kinase inhibitor in the treatment of a rare form of ovarian cancer; learn molecular biology, pharmacology, and genomic analysis skills.
Individuals with a PhD degree in cancer biology, molecular biology, pharmacology, immunology, or related fields. A strong background in pre-clinical translational research and/or molecular pharmacology is required. Experience with rodent studies is desirable but not required. Candidate should have strong organizational skills and the ability to prioritize and manage multiple projects. Proven track record of publications, excellent written and oral communication skills are required.
Interested applicants should send a Cover Letter specifying past research experience/skills/accomplishments, a Curriculum Vitae and the contact information of three (3) Referees to Dr. Robert Tyler Hillman at [email protected] with the subject line entitled “Postdoctoral Fellow - Application – Applicant’s Name”.
Consideration of applications will begin immediately and continue until the position is filled.
Stipend: Stipend support will follow the NIH Kirschstein-NRSA stipend levels level for the appropriate PGY.
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html