Research Fellow in Biochemistry/Biophysics

University of Leeds

Leeds, United Kingdom

ID: 7107191 (Ref.No. FBSMB1232)
Posted: August 4, 2022

Job Description

Are you an ambitious researcher looking for your next challenge? Do you have an established background in biochemistry, biophysics or structural biology? Do you want to further your career in one of the UKs leading research intensive Universities?

In collaboration with the investigator team (Professor David Brockwell and Dr Theo Karamanos and collaborators) you will design and perform a range of experiments to understand how TonB, which is tethered to the energised inner membrane of Gram negative bacteria, drives luminal opening of a family of outer membrane transport proteins, allowing for the import of scarce but vital nutrients. As TonB Dependent Transporters (TBDT) are virulence factors, understanding how to inhibit their function opens the door to novel antibacterial therapies.       

For this role, you should have a PhD (or close to completion) in biophysics or biochemistry or a closely allied discipline. You should also have experience in one of the following: using single molecule force spectroscopy, single molecule fluorescence or NMR to investigate protein structure or dynamics. Experience in molecular biological methods, bacterial microbiology or protein expression and characterisation is also required.

To explore the post further or for any queries you may have, please contact:  

Professor David Brockwell, Professor of Biochemistry and Molecular Biology  

Email: [email protected]  

Tel: +44(0)113 343 7821    


Location:  Leeds - Main Campus
Faculty/Service:  Faculty of Biological Sciences
School/Institute:  School of Molecular & Cellular Biology
Category:  Research
Grade:  Grade 7
Salary:  £34,304 to £40,927 p.a.
Due to funding limitations, it is unlikely an appointment will be made above £37,467 (external funding)
Working Time:  100% - we are open to discussing flexible working arrangements
Post Type:  Full Time
Contract Type:  Fixed Term (36 months - with a latest start date of 1st October 2022)
Release Date:  Wednesday 03 August 2022
Closing Date:  Saturday 03 September 2022
Reference:  FBSMB1232


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