The Department of Cell Biology has an outstanding opportunity for a Staff Research Assistant Supervisor focused on cell biology and human genetics. This position is perfect for you if you’re interested in a long-term lab manager position supervising others.

About the Van De Weghe Lab: The laboratory conducts NIH-funded research focused on understanding how the cellular organelles, cilia, work normally and what goes wrong in disease. We employ both human cell systems and the green algae, Chlamydomonas, to probe function of ciliary proteins. We use microscopy, genome engineering, biochemical isolation of cilia, functional assays, and molecular biology approaches. We’re a new group committed to fostering diversity in the fields of cellular biology and genetics. We’re looking for an enthusiastic addition to our growing group. Come join us as we tackle exciting questions in Cell Biology.

Duties:

• Conducts ongoing research projects, and may serve as a functional lead to other research staff.
• Conducts research and laboratory analysis for research staff, to include but not limited to measure and weigh compounds and solutions, isolate, identify and prepare specimens, and collect samples and other research information.
• Collects various forms of data pertaining to the research project or projects.
• Conducts data analyses, interprets data, draws conclusions, and discusses with principal investigator.
• Keeps detailed logs of all research related projects or activities.
• Conducts literature searches.
• Prepares various reports containing descriptive, analytical, and evaluative content that may be submitted for publication.
• Responsible for designing research studies.
• Collaborates with other researchers or colleagues.
• Participates in meetings and presents research findings to fellow researchers and Principal Investigator.
• Supervises a staff of research assistants and technicians.
• Responsible for training, delegating, and overseeing work.
• Discusses disciplinary action with the supervisor and Human Resources.
• Performs various duties as needed to successfully fulfill the function of the position.

Specific job duties include but are not limited to:

• Tissue culture: Maintain human cell lines using sterile techniques.
• Chlamydomonas culture: Maintain algae using sterile techniques.
• CRISPR/Cas9 genome engineering: Use genome engineering techniques to model disease variants and introduce fluorescent proteins.
• Microscopy: analyze cell lines for defects using immunofluorescence, live cell tracking.
• Basic molecular biology techniques: nucleic acid isolation, PCR, qPCR, western blotting and other established techniques.
• Expertise: Stay up to date on research related to their projects by reading the literature and attending selected seminars.
• Perform other research duties as required such as: protocol implementation and troubleshooting.
• Data Presentation: summarize research results in presentations for lab meetings as well as for use in public presentations and publications.
• Interprets and analyzes data and discusses with principal investigator.
• Maintain appropriate research documentation and databases.
• Lab Safety: Support strict lab safety practices as related to wet chemicals, compressed gases, tissue culture, and hazardous materials, and support the laboratory's compliance with federal and state safety regulations.
• Ordering: Ensure that all supplies for the lab are stocked accordingly.
• Lab organization: Help keep the laboratory tidy and organized.
• Performs other duties as assigned to successfully fulfill the function of the position.