Why Patients Need You

Everything we do, every day, is in line with an unwavering commitment to the quality and the delivery of safe and effective products to patients. Our science and risk-based compliant quality culture is flexible, innovative, and customer oriented. Whether you are involved in development, maintenance, compliance or analysis through research programs, your contribution will directly impact patients.

What You Will Achieve

We are seeking a highly motivated scientist to join the Flow Cytometry Technology Center supporting all therapeutic areas at Pfizer, Kendall Square. This individual will support scientists across multi-disciplinary backgrounds in helping them achieve the best results from their flow cytometry experiments. The qualified candidate will also perform their own research using cutting edge instrumentation and methodologies to support various functional areas. As such, the successful candidate should have an extensive background in flow cytometry instrumentation and troubleshooting, high-parameter panel development, cell sorting and expertise in assay design and analytical interpretation of results. The Senior Scientist role will require strong interpersonal skills and the successful candidate should have a history of performing innovative and high-quality work in a flow cytometry lab setting.

How You Will Achieve It

Assist and train scientists from various research units on all aspects of flow cytometry including flow cytometry instrument startup, acquisition, troubleshooting, data transfer and proper analysis and reporting.

Work with and train other members of the Technology Center staff on various concepts and methodologies pertaining to flow cytometry such as spectral cytometry, assay development and cell sorting.

Develop complex cells staining panels of 30+ colors for use by various groups and teams as well as the candidates own project support work and present these concepts and findings in small groups.

Perform cell sorting in both a low and high-parameter fashion for both service to our many users and the candidates project support work.

Involved in planning, optimizing and performing cell-based bioassays (phenotypical and functional) to support early and late-stage research projects across the organization.

Analyze and present complex high-dimensional data using dimensionality reduction tools, such as OMIQ. The successful candidate will also work with other scientists to teach and assist in how to thoughtfully plan, run and analyze/visualize these complex, high-dimensional assays.

Stay on top of innovative flow cytometry technologies, methods and developments to be an integral part of a leading technology center in the field.

Develop workshops and present in small groups to educate many scientists on the diverse topics of flow cytometry.

Qualifications

Must-Have

Master’s Degree in Science with 7+ years’ experience, or bachelor’s degree with 9+ years’ experience.

5+ years’ experience in Flow Cytometry

Expertise with BD flow cytometers and cell sorters, among other manufacturer instruments and their associated software

Experience with spectral flow cytometry and instrumentation such as Cytek Aurora cytometer.

Expertise with FlowJo and OMIQ analytical software

Be a knowledge base for all things related to flow cytometry to assist users in understanding the fundamentals of the technology and be a resource for acquiring, analyzing and correctly interpreting results

Familiarity with scientific methods associated with working in a BL2 lab atmosphere such as: aseptic technique, cell culture, sample preparation and using the instrumentation and tools related to this type of work

Effective verbal and written communication skills

Proficiency with personal computers, including word processing, Excel, PowerPoint, and relevant scientific software

Demonstrated ability to work in a team setting to develop positive working relationships and accomplish results to inform project teams on making next-step decisions

Nice-to-Have

Previous experience working in a flow cytometry core lab or shared resource laboratory.

Proven record of leading research using innovative flow cytometry technology to drive scientific projects forward.

Previous experience working with high-dimensional flow panels exceeding 25 colors.

5+ years of experience in drug discovery or development for inflammatory or autoimmune indications

Non-Standard Work Schedule, Travel, Or Environment Requirements

Work Location Assignment: On Premise