Summary

Dr. Putluri's lab is applying mass spectrometry technology to study metabolic profiling studies in cancer development and progression. Our lab established a robust research program in bladder cancer research. Particularly, we have characterized metabolic alterations associated with smoking in bladder cancer, health disparity and defined a role xenobiotic metabolism in bladder cancer progression. We use a variety of pre-clinical models including cancer cell lines, Organoid cultures, patient-derived xenografts (PDXs), and genetically engineered mouse models (GEMM). We are seeking highly motivated Staff Scientist, who is interested in translational tumor research.

Job Duties

• Collect, compile and analyze data.
• Prepare and conduct laboratory research experiments.
• Collaborate with scientists out of the lab for multidisciplinary study.
• Develop new model and technique to support the cancer-related research in the lab.
• Operate all the mass spectrometry instrumentation needed for the projects (training will be provided as needed).
• Document experimental procedures in precise details.
• Collect and compile imaging data.
• Assist in day to day operation of running scientific research lab.
• Attend Lab Meetings.
• Study epigenetic mechanisms using in vitro, ex vivo, and in vivo models.
• Conduct independent research in the field of cancer metabolism.
• Seek external funding via grants applications/submissions.
• Conduct literature searches and summarize information in an appropriate format for a particular study.
• Write the IACUC, IRB and IBC reports and ensure these are kept updated.

Minimum Qualifications

• Doctoral Degree. Experience may not be substituted in lieu of degree.
• Three years of post doctoral research experience.

Preferred Qualifications

• Experiences in tissue culture and basic molecular biology techniques (e.g., PCR, DNA purification, Western blot, etc.).
• Experience with handling animal models including performing/maintaining therapeutic experiments using mouse models will be plus.
• Experience with LCMS or Cancer metabolism desired.