Posted: December 1, 2022
Application Deadline: Open Until Filled
Department of Neurology
Anticipated start: Early 2023
The NeuroImmunity and Pathogenesis Laboratory led by Dr. Amanda Brown, PhD at the Johns Hopkins School of Medicine in Baltimore, Maryland is recruiting a well-trained, highly-motivated, postdoctoral fellow to lead innovative studies on the regulation of proinflammatory signaling in the central nervous system after systemic viral infection.
The lab’s last series of published findings show collectively that the human immunodeficiency virus’s invasion of the brain elicits a neuroprotective response. Interestingly, PET-neuroimaging in a model of HIV-infected humanized mice demonstrated microglia activation. In these same mice, a subset of dopaminergic neurons in the striatum also exhibited signs of a potentially activated state. These results suggest that neuronal-glial signaling is at play, however the molecular mechanisms are not known.
The laboratory uses primary human cell culture, modeling in humanized mice, sc-FISH, microscopy, neuroimaging, behavioral assays, established as well as the latest tools in molecular and systems biology to identify and interrogate cellular pathways. Additional resources are available through the JHU campus Core Facilities.
Qualifications and Expectations
There is ample opportunity to bring your unique expertise and professionalism to the team and our collaborators. Attention to your professional development is expected. The desire to advance the training goals of the laboratory is an additional asset. Candidates with a background and/or substantive experience in molecular/cellular neuroscience, and mouse behavioral assays is preferred.
Compensation and Benefits
Johns Hopkins University (JHU) is the first research university founded in 1876. Postdoctoral fellows (PDFs) have played key roles in advancing the discovery, teaching, clinical and innovation dissemination missions. To support the training and development of fellows, JHU has a university policy that requires all PDFs—regardless of their program, department, or division/school—be treated fairly and uniformly with regard to appointments, salary, and benefits. The Johns Hopkins University Postdoctoral Fellow Policy may be found on the university's
policy website. The policy ensures that all PDFs are eligible for health insurance, new child accommodations, vacation, and sick and safe leave. The policy also specifies the minimum salaries for PDFs.
Terms of Appointment
The fellowship is guaranteed for one year with the expectation of a second year of funding, contingent on review. Applicants may not be employed by another institution and are expected to be in residence for the duration of the appointment.
Please send the following before January 12, 2023 in a single email to [email protected]:
• A cover letter explaining your interest in the postdoctoral position
• Your dissertation abstract (1 page) that describes Ph.D. research objectives and main findings; a brief description of past challenges/roadblocks to conducting/publishing research may be included if desired.
• Your curriculum vita, including any personal information and a list of publications,
• The contact information of two to three referees
Johns Hopkins is committed to active recruitment of a diverse faculty and student body. The University is an Affirmative Action/ Equal Opportunity Employer of women, minorities, protected veterans and individuals with disabilities, and encourages applications from these and other protected group members. Consistent with the University’s goals of achieving excellence in all areas, we will assess the comprehensive qualifications of each applicant.