Summary

The department is looking for highly motivated candidates to join a team of physician scientists, scientists, postdoctoral fellows, technicians, and graduate students to support research on cancer immunotherapy using CAR T cells. The technician will provide responsible technical assistance in support of research projects by completing assignments requiring a basic knowledge of fundamental techniques and practices related to basic and translational research in cellular immunotherapy of cancer. The technician will work under supervision in accordance with general plans approved by the principal investigator. The primary purpose is to complete work towards Dr. Hegde’s V foundation grant, focused on completing molecular/functional profiling of gene-edited CAR-T cells, which in turn will develop an IND for this combination approach to treat pediatric brain tumors.

For more information: https://www.texaschildrens.org/find-a-doctor/meenakshi-g-hegde-md

Job Duties

• Performs research experiments to produce reliable and precise data to support scientific investigations in cell and gene therapy applications under the supervision of principal investigator
• Records and summarizes research data generated from experiments, prepare figures, and analyze for presentations and publications.
• Coordinates ordering, shipping, and receiving of research materials.
• Works on aseptic cell culture for production, maintenance and propagation of tumor lines and CAR T cells.
• Conducts genetic engineering techniques like PCR, cloning, retroviral transduction, and library preparations.
• Works on flow cytometry alongside immunological assays that includes multiplex assays, ELISA, ELISPOT and Western blotting.
• Works with small rodent models of cancer.
• Works on immunohistochemistry and associated image analysis.
• Uses office suite, instrument interfaces and other software for data collation and analysis.
• Assists in testing of research samples and administrative tasks involved in conduct of clinical trial.

Minimum Qualifications

• Bachelor's degree in a Basic Science or related field. Four years of related experience may substitute for degree requirement.
• No experience required.

Preferred Qualifications

• Bachelor's degree in Science/Biotechnology/Immunology.
• Experience in research lab is a plus.