Postdoctoral Fellow – Machine Learning / Mutagenesis, Signatures, and Molecular Interactions

H. Lee Moffitt Cancer Center

Tampa, FL

ID: 7120656 (Ref.No. 51009)
Posted: January 9, 2023
Application Deadline: Open Until Filled

Job Description

Moffitt Cancer Center and Research Institute is proud to be Florida’s only National Cancer Institute-designated Comprehensive Cancer Center located in Tampa. We strive to be the leader in understanding the complexity of cancer through team science and applying those insights for human benefits. Every Team Member of Moffitt focuses on our lasting commitment to our mission: To contribute to the prevention and cure of cancer.

We seek a creative and motivated postdoctoral researchers with background in machine learning and (ideally) computational chemistry to join the team of Dr. Aleksandra Karolak. Our current projects focus on the role of DNA and proteins sequence and structure on the mutagenesis, genomic organization, tumor progression in cancer; furthermore, we are interested in repurposing and design of novel therapeutics.
If your background overlaps and if you are interested in one of the projects focusing on 1) understanding the molecular aspects of mutagenesis, responses to treatment, genome conformation, and/or tumor topology across the genomes and populations, or 2) molecular interactions (protein-protein, protein-DNA, protein-small molecules) and identification of novel compounds to treat cancer – we encourage you to apply. We have exciting opportunities for you within our team at the institution that will strongly support your scientific growth and future successes.
The Computational Oncology Group in the Machine Learning Department at Moffitt combines multidisciplinary and multiscale approaches from the fields of chemistry, structural biology, machine learning, information theory, and mathematical oncology, to advance cancer research. We collaborate with the Departments of Gastrointestinal Oncology, Molecular Medicine/Drug Discovery, Population Science, Bioinformatics&Biostatistics, and Mathematical Oncology. We also actively collaborate with the extramural oncology centers and academic institutions.
To learn more about the exciting work being done visit:
Position Highlights:
• Moffitt integrates excellent patient care with cutting-edge clinical and basic research. Having a cancer hospital on-site provides unique opportunities for translational research.
• The position is essential for development of comprehensive tools benefiting basic to clinical research through identification of novel approaches and biomarkers to treat cancer, and improved stratification of cancer patients.
• The position offers vibrant and interactive work environment in the Quantitative Science Division and results will bring value beyond the community of Moffitt patients.
• Outstanding mentorship from expert faculty with wide-ranging funded research programs including T32 Training Grants.
• You will be encouraged and supported to apply for training grants.

The Ideal Candidate:
• High motivation and desire to be part of multidisciplinary group, good work ethic.
• Excellent interpersonal and communication skills (written and verbal).
• Documented experience with machine learning concepts, tools, and applications.
• High proficiency with at least one of the programming languages and statistical packages.
• Deep knowledge of biological data sources and databases.
• Experience with concepts and applications from computational chemistry of proteins, DNA, or other systems.
• Preferable knowledge of cancer biology.
• Experience with extraction, handling, and processing of large data sets.

• Data preparation, organization, and analysis.
• Development of new and tuning of existing models and analytical approaches.
• Presentation of data and results in a clear and concise manner.
• Active participation in the group meetings and meetings with the collaborating teams.
• Ability to work with the team and independently.
• Supervision of undergraduate and graduate students.
• Preparation of grant applications, publications, and presentations.
• Meeting project goals.

Credentials and Qualifications:
• Ph.D. degree and research experience in the fields of machine learning, computer science in biomedical applications or related field of study.
• At least one first-author publication.

Interested applicants should submit a current CV with recent publications, a cover letter summarizing their research training and accomplishments, and contact information for three references.

You will be eligible for benefits offered to our Team Members – Moffitt Postdocs are provided free employee-only Medical and eligible for Dental, Vision, Paid Time Off, Retirement, Parental Leave, and more. With a move to Tampa, you may be eligible for relocation allowance. Reason to relocate, aside from the sunshine, beaches and year-round outdoor recreation associated with the Gulf Coast of Florida, Tampa is a thriving metropolitan city with unique cultural attractions, low cost of living and a high quality of life. We strive for work/life balance.

If you have the vision, passion, and dedication to contribute to our mission,
then we have a place for you.

Equal Employment Opportunity
Moffitt is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, or protected veteran or disabled status. Moffitt seeks candidates whose skills, and personal and professional experience, have prepared them to contribute to our commitment to diversity and excellence.

Mission To create a Moffitt culture of diversity, equity, and inclusion as we strive to contribute to the prevention and cure of cancer. Vision To advance and accelerate a culture of access, equity, and inclusion. Diversity is a priority at Moffitt and is meant "to promote a culture of diversity and inclusion as we contribute to the prevention and cure of cancer." The Enterprise Equity Department focuses its efforts on eliminating those obstacles to an individual’s ability to exist within their personal comfort zone at the cancer center. Everyone is important to meeting this priority. Addressing and responding to diversity and inclusion fosters an environment where mutual respect for diverse cultures, communication styles, languages, customs, beliefs, values, traditions, experiences and other ways in which we identify ourselves, is the expectation.