Positions are available immediately at the level of either Postdoctoral Research Fellow and/or Junior Faculty for investigators with a strong interest in studies exploring new pathways involved in cardiovascular and metabolic diseases. Major research programs in the laboratory focus on the interface between gut microbiome and cardiometabolic diseases; and therapeutic drug development efforts of these pathways. We are especially seeking persons with microbiome, microbial enzymology and biochemistry skill sets. Animal handling experience is a plus. 

The Hazen laboratory uses multidisciplinary approaches to study mechanisms through which gut microbiota contribute to cardiometabolic diseases and related inflammatory disorders. The laboratory is housed within the Lerner Research Institute, on the Cleveland Clinic campus. Research programs span from “bench-to-bedside”, including mechanistic studies involving genetically engineered microbes, recombinant microbial enzymes, host receptor-microbial-derived metabolite biological responses, animal models of disease, large scale human clinical studies, and both animal model and human interventional investigations. 

The research program is well funded and highly productive, with frequent publications in both clinical and basic top tier research journals alike. Our research team has broad expertise and background, and includes both analytical and synthetic chemists, numerous basic scientists (biochemistry, genetics, cellular and molecular biology, physiology) and both translational and clinical researchers.  Candidates need to be self-motivated individuals with excellent work ethic, organizational and communication skills. Background in microbiology, gut microbiota related / relevant research, animal models is a plus.

Principal Investigator: Stanley Hazen, MD, PhD

Lerner Research Institute Department: Cardiovascular & Metabolic Sciences

Lab Research Topics:

• Cardiometabolic diseases
• Gut microbiome
• Inflammatory disorders
• Therapeutic drug development
• For more information about the lab’s research, please visit: https://www.lerner.ccf.org/cardiovascular-metabolic/hazen/ or contact Taylor Weeks at [email protected] or Dr. Hazen at [email protected]

Job Responsibilities:

• Independent project design with the goal of data generation, analysis, interpretation and manuscript preparation
• Perform research related to the microbiome, microbial enzymology, and biochemistry
• Collaborate with other lab members on additional research projects
• Participate in regular lab meetings and departmental presentations

Education:

• PhD or MD/PhD required
• MD with relevant laboratory experience may substitute for PhD

Languages:

• English Proficiency proof required for candidates arriving on J-1, J-2, or F1 + OPT visa status

Work Experience:

• Previous experience in a research or academic setting.  Graduate student experience meets this requirement.
• Scientific writing experience

Additional Preferred Qualities:

• Experience with microbial enzymology and/or biochemistry
• Animal handling experience preferred
• Background in microbiology and gut-microbiota related research preferred

Physical Requirements:

• Ability to perform work in a stationary position for extended periods
• Ability to operate a computer and other office equipment
• Ability to communicate and exchange accurate information
• Ability to distinguish color
• Manual dexterity to handle specimens and repair equipment
• Ability to lift and transport equipment or specimens weighing up to 20 pounds
• May be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc.

Personal Protective Equipment:

• PPE per institutional requirements; may vary by laboratory

Preferred Application Materials:

All application materials should be submitted directly via email to Taylor Weeks at [email protected].

• CV
• Names/contact info for 3 references

Keywords: Postdoc, Research, LRI, Gut microbiome, Animal models, Mechanistic research, Drug development research, Microbiology, Translational research, Cardiovascular diseases, Biochemistry, Microbial enzymology