University of Michigan

Ann Arbor, MI

ID: 7145332
Posted: May 15, 2023
Application Deadline: Open Until Filled

Job Description

The Wilcox Laboratory in the Department of Internal Medicine, Division of Hematology/Oncology at the University of Michigan Medical School and Rogel Cancer Center is seeking a postdoctoral fellow to join a translational research group investigating the tumor microenvironment’s role in T-cell lymphomas. Unfortunately, most patients afflicted with these lymphomas will ultimately succumb to their disease. Improved understanding of T-cell lymphoma pathogenesis and the development of novel therapeutic strategies will be needed to address this challenge and improve outcomes for patients afflicted with these aggressive lymphomas. Our group investigates the role of tumor microenvironment dependent factors (e.g. antigen, costimulation, cytokines) and transcriptional programs (e.g. GATA-3) that promote T-cell lymphomagenesis. The laboratory uses complementary mouse models and primary T-cell lymphoma specimens (in ex vivo and patient-derived xenograft studies) to address these fundamental and clinically relevant questions and is poised to clinically translate laboratory-based findings into novel therapeutic strategies. The lab has room for up to two new postdoctoral fellows.

Pursue full-time, laboratory-based research investigating fundamental mechanisms regulating the binding of relevant transcription factors to chromatin and their respective target genes; read deeply in the relevant scientific literature; prepare manuscripts for publication and present research at national meetings.

Required Qualifications*
We seek a self-motivated individual with a Ph.D. in molecular biology (or related biomedical discipline) with a strong intellectual commitment to understanding molecular mechanisms of disease and enthusiasm for multidisciplinary research.

Desired Qualifications*
A background in chromatin biology and/or transcriptional regulation is preferred.

Background Screening
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline
Job openings are posted for a minimum of seven calendar days. This job may be removed from posting boards and filled anytime after the minimum posting period has ended.