Research Fellow in immunometabolism and inflammation

University of Leeds

Leeds, United Kingdom

ID: 7184108 (Ref.No. MHLRM1234)
Posted: October 3, 2023

Job Description

Are you an ambitious researcher looking for your next challenge?  Do you have a background in immunometabolism and macrophage/monocyte biology.  Do you want to further your career in one of the UK’s leading research intensive Universities?


This post is funded from a senior fellowship grant awarded to associate professor Dr Sinisa Savic. The aim of the fellowship is to investigate the role of post-zygotic, somatic mutations in the pathogenesis of various immune mediated inflammatory diseases and their influence on response to treatment. There are already well-established collaborations, locally, nationally and internationally to ensure that post holder will have access to rich, unique, and well-defined patient cohorts. Furthermore, there are established links with NIHR-BioResource, Leeds NIHR Biomedical centre and UK Biobank. The post holder will be working closely with another PDFR, two research technicians, one PhD students and one clinical fellow to deliver objectives of this project. The post holder will be expected to develop functional assays to validate effects of novel genetic findings on immunometabolism and inflammatory function of myeloid cells. Previous experience in immunology, use of techniques such as Seahorse XF Analyzer, carbon tracing, LC-MS and polar metabolomics, CRISPR-Cas9 genome editing or lentiviral plasmid transduction to manipulate and study immunometabolism of myeloid cell lines is essential. 

To explore the post further or for any queries you may have, please contact: 

 Dr Sinisa Savic 

Email: [email protected]

As an international research-intensive university, we welcome students and staff from all walks of life and from across the world. We foster an inclusive environment where all can flourish and prosper, and we are proud of our strong commitment to student education. Within the Faculty/School of Medicine we are dedicated to diversifying our community and we welcome the unique contributions that individuals can bring, and particularly encourage applications from, but not limited to Black, Asian, people who belong to a minority ethnic community, people who identify as LGBT+; and disabled people.  Candidates will always be selected based on merit and ability.  

Location:  Leeds - St James University Hospital
Faculty/Service:  Faculty of Medicine & Health
School/Institute:  Leeds Institute of Rheumatic & Musculoskeletal Medicine (LIRMM)
Category:  Research
Grade:  Grade 7
Salary:  £37,099 to £44,263 p.a.
Working Time:  100% Full time Equivalent
Post Type:  Full Time
Contract Type:  Fixed Term (Available until 31st December 2027 due to external grant income)
Release Date:  Monday 02 October 2023
Closing Date:  Monday 16 October 2023
Reference:  MHLRM1234

The University community is made up of a wide range of people with diverse backgrounds and circumstances, which we value and regard as a great asset. As part of our continued commitment to equality and inclusion, we strive to create an environment where everyone can reach their full potential and have a real opportunity to participate in and contribute to our activities.