Research Associate II - Cancer Cell Lines and Mouse Models

City of Hope

Duarte, CA

ID: 7199750 (Ref.No. 10024094)
Posted: 3 months ago
Application Deadline: Open Until Filled

Job Description

Join the forefront of groundbreaking research at theBeckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

Under the supervision of Dr. Heather McGee, the Research Associate II will contribute to research projects focused on studying the immune response to radiation. Dr. McGee’s research is currently supported by an NIH R00 grant from the National Cancer Institute, the AACR-Debbie’s Dream Award for Gastric Cancer Research, the City of Hope Chancellor’s Award and a start-up package from City of Hope. Research findings from Dr. McGee and colleagues have been published in Nature, Nature Communications, Clinical Cancer Research, Journal of Immunology, Journal for Immunotherapy of Cancer, International Journal of Radiation Oncology* Biology* and Physics, and numerous other journals.

As a successful candidate, you will:

· Serve as lab manager, responsible for ordering supplies/maintaining inventories of supplies, updating the lab’s IACUC, IBC and other protocols, and genotyping mice/ maintaining the lab’s mouse colony.

· Assist other scientists in the lab with a variety of research experiments, including culturing and irradiating tumor cell lines, performing molecular biology assays, performing in vivo murine experiments, harvesting murine tumors and isolating immune cells, and using FACS to characterize immune cell populations.

· Be responsible for analyzing data using Flow Jo, ImageJ and Prism software, as well as compiling results and preparing presentations for lab meetings.

· Utilize established protocols to perform a variety of in vitro experiments (in cancer cell lines) and in vivo experiments (in murine tumor models) under the guidance of senior scientists in the lab.

· Update IACUC, IBC and IRB protocols for the lab.

· Update laboratory experimental protocols for the lab.

· Genotype mice and help maintain the lab’s mouse colonies.

· Bachelor’s degree. Masters degree preferred

· 2+ years of related research/laboratory experience with a Bachelor’s degree or 1+ year related research/laboratory experience with a Master’s degree.

· Experience with flow cytometry and tumor immunology is preferred.

· Experience with cell culture and murine tumor models is preferred.

City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity and inclusion, please click here

The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.



City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.