About Us:
The Wyss Institute’s mission is to transform healthcare and the environment by emulating the way nature builds. We harness the freedom of academia and the focus of industry in order to translate revolutionary technologies into commercial products and solutions. At the Wyss Institute, faculty from premier academic and clinical institutions, collaborate with staff scientists, postdocs, graduate students, industry experts, business development leaders, and entrepreneurs across disciplines to invent and de- risk new technologies that don’t just succeed at making it to the market – they disrupt it. We support research that universities, companies, and venture capital firms don’t fund because they view it as too risky. We prefer to use the word “challenging,” and we love challenges. For more information, visit: http://wyss.harvard.edu/

About You:
You are a collaborative, impact-focused problem solver who wants to be part of a dynamic team dedicated to creating and commercializing novel approaches to global challenges in healthcare and sustainability. You want the opportunity to explore your scientific interests and apply your knowledge to tackle ambitious projects in a fast-paced, entrepreneurial-minded environment with resources and support from top-notch scientific operations and administrative professionals. You will have significant expertise in developing machine learning methods to engineer proteins with non-standard amino acids for therapeutic applications. You enjoy working with diverse groups of people and leveraging your expertise to create innovations that can change the world.

About the Role:
We are looking for an innovative Scientist to join the AminoX team as the primary member of the research and development team responsible for generating the scientific and technical results to support a commercialization end-point. Reporting Director, Synthetic Biology and collaborating closely with the AminoX project team and faculty and Wyss Business Development, you will help drive the scientific program forward, in accordance with the agreed-upon project goals and timelines. As a translational institute and member of our Advanced Technology Team, you will be collaborating with various project teams and exposed to many different technologies in areas ranging from therapeutics and diagnostics to synthetic biology and materials science. You may also have the unique opportunity to transition into a newly formed start-up company.

What You'll Do:
Design deep learning models to engineer proteins to develop a new class of non- standard amino acid-based therapeutics
Design and conduct computational experiments, analyze data, and propose candidate acceptance criteria for testing and validation of candidate targets.
Present key results at group meetings, project teams, and stakeholders
Contribute to internal reports, scientific publications, and intellectual property filings
Actively supports and collaborates with other areas of the Synthetic Biology platform and the Advanced Technology Team as it relates to new technology
development, community building, administrative efficiencies, and operational protocols.
Demonstrate a commitment to diversity, inclusion and cultural awareness through interactions and communications with others.

Basic Qualifications :
Bachelor’s degree in Computer Science, Computer Engineering, Bioinformatics, BioEngineering, synthetic biology or related discipline
A minimum of 4 years of experience in machine learning, protein design, and/or synthetic biology

Additional Qualifications and Skills :
PhD in BioEngineering, Computational Drug Design, or Machine Learning, strongly preferred
Expertise in protein engineering for therapeutic applications is strongly preferred
Strong understanding of fundamental concepts in protein design
Experience with Python or Matlab is preferred
Experience in authoring and critically reviewing technical documents, study protocols and reports related to assay development, qualification, validation, and clinical sample testing a plus.
Excellent written and verbal communication skills, documentation skills and attention to detail, with the proven ability to work effectively as a member of a multidisciplinary team
Full-time post-graduate industry experience with a focus on product development is preferred.
Experience with the design, engineering, and production of protein modeling is strongly preferred
Expertise in non-standard amino acid design is strongly preferred

Additional Information :
This is a term position ending on June 30, 2025 with the possibility of renewal

Why you’ll like working with us:
At the Wyss Institute, you’re a member of a supportive, dynamic community that is united by its shared goal of changing the world through groundbreaking technology development and commercialization. We encourage your professional growth and development through mentorship and tuition reimbursement to support continued learning, and more. We also support your physical, financial, and mental well-being through generous time off benefits, gym reimbursements, and other programs offered through Harvard. Our facility is located in a new, state-of-the-art life sciences building in the lively Fenway neighborhood, where you have access to multiple amenities including a roof top terrace with stunning views of Boston and proximity to numerous restaurants and cultural attractions. We value an inclusive and diverse workforce, and believe that our differences enrich the work environment for all.